Our goal is to use eDNA approaches to monitor life more accurately in the global ocean. With an initial focus on the continental Australian Commonwealth marine estate. Our vessel the Pangaea Ocean Explorer has capabilities for onboard genomic analyses. OceanOmics is creating resources that enable broad scale deployment of marine eDNA, including reference library generation for marine vertebrates; novel methods for monitoring and combating threats to marine wildlife and ecosystems; quantifying the health status of current marine protected areas (MPAs); and assisting governments and management agencies in identifying new biodiversity hotspots and ecosystems in need of protection.